Tirzepatide — dosage chart

Tirzepatide is a dual GIP/GLP-1 receptor agonist marketed as Mounjaro and Zepbound for type 2 diabetes and chronic weight management. The figures below reproduce the published FDA label for reference only and are not a dosing recommendation.

⚕️ For information only — not medical advice. This medicine is prescription-only. The figures shown reproduce published prescribing information and study data and are not a dosing recommendation. Use and dosing only under medical prescription. This information has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.

mg → units reference (math only)

Pure arithmetic for the example reconstitution below: how many units on a U-100 insulin syringe a given dose corresponds to. units = doseMg ÷ (vialMg ÷ bacMl) × 100. These are unit conversions, not a dosing recommendation.

Example reconstitution: 10 mg vial + 2 mL bacteriostatic water (5 mg/mL)
Dose	Units (U-100)	Volume
2.5 mg	50.0 U	0.500 mL
5 mg	100.0 U	1.000 mL
7.5 mg	150.0 U	1.500 mL
10 mg	200.0 U	2.000 mL
12.5 mg	250.0 U	2.500 mL
15 mg	300.0 U	3.000 mL

Published titration / dose schedule

The FDA prescribing information for Zepbound describes initiation at the starter dose with increases of 2.5 mg no sooner than every 4 weeks, up to a maximum of 15 mg once weekly:

2.5 mg weekly for 4 weeks (initiation, not a maintenance dose) → increase to 5 mg → then in 2.5 mg steps no more often than every 4 weeks: 7.5 mg → 10 mg → 12.5 mg → 15 mg maximum. Recognised maintenance doses are 5, 10 or 15 mg; the label notes the lowest effective dose should be used.

Source: FDA — Zepbound (tirzepatide) Prescribing Information

Sources

As of: June 21, 2026

Neutral tools

Need the math for your own setup? Use the neutral, drug-agnostic tools — they come with no pre-loaded "recommended" dose.

Reconstitution calculatorConvert any dose, vial size and BAC water into units to draw.Drug-level chartVisualise how an estimated level builds and decays over time.