Semaglutide — dosage & units chart

Semaglutide is a GLP-1 receptor agonist used, under the brand names Ozempic and Wegovy, for type 2 diabetes and chronic weight management. This page reproduces the published prescribing information and the mg→units math for reference only; it is not a dosing recommendation.

⚕️ For information only — not medical advice. This medicine is prescription-only. The figures shown reproduce published prescribing information and study data and are not a dosing recommendation. Use and dosing only under medical prescription. This information has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.

mg → units reference (math only)

Pure arithmetic for the example reconstitution below: how many units on a U-100 insulin syringe a given dose corresponds to. units = doseMg ÷ (vialMg ÷ bacMl) × 100. These are unit conversions, not a dosing recommendation.

Example reconstitution: 5 mg vial + 2 mL bacteriostatic water (2.5 mg/mL)
Dose	Units (U-100)	Volume
0.25 mg	10.0 U	0.100 mL
0.5 mg	20.0 U	0.200 mL
1 mg	40.0 U	0.400 mL
1.7 mg	68.0 U	0.680 mL
2.4 mg	96.0 U	0.960 mL

Published titration / dose schedule

For weight management (Wegovy), the FDA prescribing information describes a fixed 16-week escalation before the maintenance dose, raising the dose every 4 weeks to improve gastrointestinal tolerability:

0.25 mg weekly (weeks 1–4) → 0.5 mg (weeks 5–8) → 1.0 mg (weeks 9–12) → 1.7 mg (weeks 13–16) → 2.4 mg as the maintenance dose from week 17. The label states the 0.25 mg starting dose is for initiation and is not intended for glycaemic or weight effect.

Source: FDA — Wegovy (semaglutide) Prescribing Information

Sources

As of: June 21, 2026

Neutral tools

Need the math for your own setup? Use the neutral, drug-agnostic tools — they come with no pre-loaded "recommended" dose.

Reconstitution calculatorConvert any dose, vial size and BAC water into units to draw.Drug-level chartVisualise how an estimated level builds and decays over time.