{"slug":"dsip","seoKey":"dsip","inn":"emideltide","displayName":"DSIP","codes":["DSIP"],"synonyms":["delta sleep-inducing peptide","emideltide","Emideltid","emideltidum","Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu","H-WAGGDASGE-OH","Пептид дельта-сна","registered as an over-the-counter intranasal medicine in the Russian Federation since 2016 (an eighth market the registry does not track)"],"legalClass":"rx","identifiers":{"cas":"62568-57-4","pubchemCid":68816,"unii":"YN28Z5YZ73","inchikey":"ZRZROXNBKJAOKB-GFVHOAGBSA-N","chemblId":"CHEMBL2104403","wikidataQid":"Q27294600","formula":"C35H48N10O15","molecularWeight":848.8,"sequence":"WAGGDASGE"},"approvals":[{"market":"US","status":"not_approved","note":"Not approved in any indication or dosage form. Listed among the bulk drug substances that may present significant safety risks; the regulator states it has not identified safety information for the proposed route of administration. The substance register carries an approved name entry, which is a naming record and not a marketing authorisation.","source":"https://www.fda.gov/drugs/human-drug-compounding/certain-bulk-drug-substances-use-compounding-may-present-significant-safety-risks"},{"market":"EU","status":"not_approved","note":"No centralised marketing authorisation and no assessment report. The substance appears in the union product data management system only as a substance record, which is not an authorisation. No entry found on 2026-09-07.","source":"https://www.ema.europa.eu/en/medicines?search_api_fulltext=DSIP"},{"market":"DE","status":"not_approved","note":"Neither a national nor an EU marketing authorisation, and no food supplement status. Full-text checks on 2026-09-07 found it named neither in the prescription-only annex nor in narcotics legislation; that absence does not make an unauthorised medicine lawful.","source":"https://www.gesetze-im-internet.de/amvv/anlage_1.html"},{"market":"UK","status":"not_approved","note":"No marketing authorisation; treated as an unlicensed medicine and not a controlled drug. Not verified against a primary regulator document on 2026-09-07; the finding follows from the absence of any authorisation.","source":"https://products.mhra.gov.uk/search/?search=DSIP"},{"market":"AU","status":"not_approved","note":"Not named in the Poisons Standard; a full-text search on 2026-09-07 returned no entry, confirmed by a working control query that finds other peptides in the same document. No registration exists, so it remains an unapproved therapeutic good.","source":"https://www.legislation.gov.au/F2026L00633/asmade"},{"market":"CA","status":"not_approved","note":"No marketing authorisation, no drug identification number and no natural health product status. Not verified against a primary regulator document on 2026-09-07.","source":"https://health-products.canada.ca/api/drug/activeingredient/?ingredientname=DSIP"},{"market":"CH","status":"not_approved","note":"No marketing authorisation, although the substance was discovered in Basel and clinically studied there in the 1980s. Not verified against a primary regulator document on 2026-09-07.","source":"https://www.swissmedicinfo.ch/"}],"devStage":"approved","strongestEvidence":"rct_phase2","wada":{"status":"unclear","listYear":2026,"source":"https://www.wada-ama.org/en/prohibited-list"},"trials":[],"sameAs":["https://www.wikidata.org/wiki/Q27294600","https://pubchem.ncbi.nlm.nih.gov/compound/68816","https://www.ebi.ac.uk/chembl/compound_report_card/CHEMBL2104403/"],"lastVerified":"2026-09-07","version":"1.0","published":true,"locale":"en","title":"DSIP: what the studies show, status and safety","summary":"DSIP is a chain of nine amino acids found in rabbit brain blood in Basel in the 1970s. Its name is a hypothesis from 1977, not a proven effect: two independent groups found no meaningful benefit in insomnia, and the best modern study found the opposite. Russia alone licenses a nasal product containing it. No receptor is known.","updated":"2026-09-07","url":"https://mypep.app/peptides/dsip"}