{"slug":"5-amino-1mq","seoKey":"5amino1mq","displayName":"5-Amino-1MQ","codes":["5A1MQ","5-AMQ","Compound 1k"],"synonyms":["5-amino-1-methylquinolinium","5-amino-1-methylquinolin-1-ium","small molecule, not a peptide (quinolinium scaffold, no amino acid sequence)","NNMT inhibitor (nicotinamide N-methyltransferase)","5-amino-1-methylquinolinium iodide (iodide salt, CAS 42464-96-0, PubChem CID 66522933)","5-amino-1MQ monochloride (chloride salt used in animal studies)"],"legalClass":"research_chemical","identifiers":{"cas":"685079-15-6","pubchemCid":950107,"unii":"PMX593N4N3","inchikey":"ZMJBCEIHNOWCMC-UHFFFAOYSA-O","chemblId":"CHEMBL4116828","formula":"C10H11N2+","molecularWeight":159.21},"approvals":[{"market":"US","status":"not_approved","note":"Not approved in any indication, no pharmacopoeial monograph and not a recognised dietary supplement ingredient. Not listed on any compounding bulk drug substances list; the full text of that page was checked on 2026-09-06.","source":"https://www.fda.gov/drugs/human-drug-compounding/certain-bulk-drug-substances-use-compounding-may-present-significant-safety-risks"},{"market":"EU","status":"not_approved","note":"No authorised medicinal product and no monograph in the European Pharmacopoeia. Marketed as a food it would be a novel food requiring authorisation. No entry found on 2026-09-06.","source":"https://www.ema.europa.eu/en/medicines?search_api_fulltext=5-amino-1MQ"},{"market":"DE","status":"not_approved","note":"No national or EU marketing authorisation; a substance with a medicinal purpose may not be placed on the market without one. Not named in narcotics or new psychoactive substances legislation. No entry found on 2026-09-06.","source":"https://www.ema.europa.eu/en/medicines?search_api_fulltext=5-amino-1MQ"},{"market":"UK","status":"not_approved","note":"No marketing authorisation and no substance-specific rule found. No entry found on 2026-09-06.","source":"https://products.mhra.gov.uk/search/?search=5-amino-1MQ"},{"market":"AU","status":"not_approved","note":"Not named in the Poisons Standard; the full text was searched on 2026-09-06 for the substance name, the scaffold and the enzyme name without a hit. Absence of a listing does not make an unapproved therapeutic good freely available.","source":"https://www.legislation.gov.au/F2026L00633/asmade"},{"market":"CA","status":"not_approved","note":"No marketing authorisation and no drug identification number. No entry found on 2026-09-06.","source":"https://health-products.canada.ca/api/drug/activeingredient/?ingredientname=5-amino-1MQ"},{"market":"CH","status":"not_approved","note":"No marketing authorisation. No entry found in the Swiss medicinal product information on 2026-09-06.","source":"https://www.swissmedicinfo.ch/"}],"devStage":"preclinical","strongestEvidence":"animal","wada":{"status":"prohibited","section":"S0","listYear":2026,"source":"https://www.wada-ama.org/en/prohibited-list"},"trials":[],"sameAs":["https://pubchem.ncbi.nlm.nih.gov/compound/950107","https://www.ebi.ac.uk/chembl/compound_report_card/CHEMBL4116828/"],"lastVerified":"2026-09-06","version":"1.0","published":true,"locale":"en","title":"5-Amino-1MQ: what the studies show, status and safety","summary":"5-Amino-1MQ is not a peptide. It is a small synthetic molecule with no amino acids in it, and it blocks an enzyme called NNMT that processes a breakdown product of vitamin B3. It appears in this peptide register because it is marketed as a peptide and sold beside them. Not one study in people exists. The animal work comes almost entirely from one research group and the company founded out of it, and the substance has never been through a safety programme of any kind.","updated":"2026-09-06","url":"https://mypep.app/peptides/5-amino-1mq"}